Which method is used in conjunction with cytology for HPV detection?

Prepare for the AAB Molecular Diagnostics Test with focused study materials and practice questions. Gain insights into questions, formats, and key topics to excel in your exam and advance your career in molecular diagnostics.

The method that is used in conjunction with cytology for HPV detection is the liquid PAP smear. This technique improves the collection and preservation of cervical cells, allowing for more accurate cytological evaluation. In a liquid-based cytology (LBC) process, the collected sample is placed in a liquid preservative, which helps to disperse the cells evenly, enhancing the detection of abnormalities that may suggest HPV infection.

Liquid PAP smears are particularly valuable because they not only allow for traditional cytological examination but also facilitate additional testing for HPV directly from the same sample, providing a comprehensive assessment of the presence of HPV and any associated cellular changes. This dual functionality enhances diagnostic efficiency and is a more sensitive method of detecting both cytological abnormalities and HPV compared to conventional smears.

Other methods like ultrasound imaging, lipid profile tests, or blood cultures are unrelated to HPV detection or cytology, as they serve different purposes in clinical diagnostics. Therefore, recognizing the specific use of liquid PAP smear in HPV context helps reinforce its significance in molecular diagnostics.

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