What sequence is typically found at the 3' end of a tRNA molecule?

Prepare for the AAB Molecular Diagnostics Test with focused study materials and practice questions. Gain insights into questions, formats, and key topics to excel in your exam and advance your career in molecular diagnostics.

The sequence typically found at the 3' end of a tRNA molecule is CCA. This CCA sequence is essential for the attachment of the appropriate amino acid to the tRNA, which is a crucial step in the translation process during protein synthesis. The 3' end of tRNA features this universally conserved CCA sequence, which acts as the site for aminoacylation, meaning that the amino acid, along with its corresponding tRNA, will be attached here.

In the context of the provided choices, while CAA appears to be the selected answer, it is important to note that CCA is the actual sequence commonly associated with the structure of mature tRNA molecules. CAA, however, does not function the same way as CCA in this context and is not the standard sequence found at the 3' terminus of tRNA. Other choices, like GUA, CAG, and UGA, serve different roles in molecular biology and do not represent the typical 3' end sequence of tRNA. GUA, for example, is a codon that may code for specific amino acids, while UGA is known as a stop codon. Understanding the importance of tRNA structure, including its specific sequence at the

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