What type of leukemia is associated with a translocation feature?

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Chronic myelogenous leukemia (CML) is characterized by a specific genetic translocation known as the Philadelphia chromosome, which results from a fusion between the BCR gene on chromosome 22 and the ABL gene on chromosome 9. This fusion creates the BCR-ABL tyrosine kinase, a hallmark of CML, and is crucial for both the diagnosis and the understanding of the disease mechanism.

The presence of this translocation is not only a diagnostic criterion but also a target for specific therapies, such as tyrosine kinase inhibitors, which have significantly improved treatment outcomes for patients with CML. In contrast, other types of leukemia listed do not have a definitive translocation that is universally recognized as a hallmark feature. While acute lymphoblastic leukemia may also involve translocations, it's not as characteristic as the Philadelphia chromosome in CML. Therefore, the translocation feature specifically points to chronic myelogenous leukemia as the correct answer.

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