Which of the following sequences is not characteristic of a eukaryotic polymerase II promoter?

A eukaryotic polymerase II promoter typically comprises several key elements that are important for the initiation of transcription. Among the options provided, the sequence that is not characteristic of this type of promoter is indeed the TTGACA sequence.

The TATAAA box, commonly referred to as the TATA box, is a well-known core promoter element found in many eukaryotic promoters that helps position the RNA polymerase II enzyme for transcription initiation. It is usually located about 25 to 30 base pairs upstream of the transcription start site.

The CAAT box is another important sequence element that can be found in eukaryotic promoters. It is generally located further upstream and plays a role in enhancing the transcriptional activity of that promoter.

Similarly, a GC-rich box is associated with many eukaryotic promoters, particularly those that are constitutively active. This element contains a high frequency of guanine (G) and cytosine (C) residues, which can also contribute to the regulation of gene expression.

In contrast, the TTGACA sequence is a characteristic sequence found in prokaryotic promoters, specifically as part of the -35 region recognized by sigma factors in bacterial RNA polymerase. This sequence does not typically appear